Manufacturer,provider and supplier of
Recombinant Human Interleukin-4,IL-4,rHuIL-4,IL4,rHuIL4

Quantity: 10ug,100ug

Description
Recombinant human IL-4 produced in Yeast is a single,glycosylated,polypeptide chain containing
129 amino acids,three pairs of disulfide bonds and having a molecular mass of approximately 15.0
kD (after glycosylation,the molecular mass is 30.0kD.)

Source  Yeast

Molecular Mass  Approximately 30.0kD.

Purity  ≥97%,as determined by SDS-PAGE and HPLC method.

Endotoxin Level  ≤1EU/μg, determined by the LAL method.

Biological Activity  Measured in a cell proliferation assay using a human factor-dependent cell line, TF-1. The specific activity shall be not less than 1X107IU/mg.

Formulation
Lyophilized from a 0.2μm filtered solution in 50mM Phosphate Buffer containing 0.1% human serum
albumin.

Reconstitution
It is recommended that sterile ddH2O containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of not less than 5ug/mL of the cytokine.

Storage
Lyophilized samples are stable for greater than six months from date of receipt at -20ºC to -70ºC.
Upon reconstitution, this cytokine can be stored under sterile conditions at 2ºC-8ºC for one month
or at -20ºC to ?0ºC in a manual defrost freezer for 3 months without detectable loss of activity.
Avoid repeated freeze-thaw cycles.

Human Interleukin 4
Interleukin 4 is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils.It was
initially identified as a B cell differentiation factor (BCDF),as well as a B cell stimulatory factor (BSF1).
Subsequent to the molecular cloning and expression of both human and mouse IL-4, numerous
other functions have been described on B cells as well as other hematopoietic and nonhematopoietic
cells,including T lymphocytes, monocytes, macrophages, mast cells, myeloid and erythroid
progenitors,fibroblasts, endothelial cells, etc. IL-4 exhibits anti-tumor effects both in vivo and in vitro.

FOR RESEARCH USE ONLY,NOT FOR HUMAN USE.